Achievement

Makoto Mizunami, Professor

1. Mizunami M., Hirohata S., Sato A., Arai R., Terao K., Sato M. and Matsumoto Y. (2019). Development of behavioral automaticity by extended Pavlovian training in an insect. Proc. R. Soc. B. 286: 20182132.

2. Hamanaka Y. and Mizunami M. (2018). Tyrosine hydroxylase-immunoreactive neurons in the mushroom body of the field cricket, Gryllus bimaculatus. Cell Tissue Res. https://doi.org/10.1007/s00441-018-2969-9.

3. Nishino H, Iwasaki M, Paoli M, Kamimura I, Yoritsune A, Mizunami M. (2018). Spatial receptive fields for odor localization. Curr. Biol. 28:1-9.

4. Koizumi M, Shigeno S, Mizunami M, Tanaka N. K. (2018) Calcium imaging method to visualize the spatial patterns of neural responses in the pygmy squid, Idiosepius paradoxus, central nervous system. J. Neurosci. Methods 294: 67-71.

5. Terao K, Mizunami M. (2017) Roles of dopamine neurons in mediating the prediction error in aversive learning in insects. Sci. Rep. 7:14694.

6. Watanabe H, Nishino H, Mizunami M, Yokohari F (2017) Two parallel olfactory pathways for processing general odor in a cockroach. Front. Neural Circuits 11: 32.

7. Katoh K, Iwasaki M, Hosono S, Yoritsune, A, Ochiai M, Mizunami M, Nishino H. (2017) Group-housed females promote asexual ootheca production in American cockroaches. Zool. Lett. 3:3.

8. Takahashi N, Katoh K, Watanabe H, Nakayama Y, Iwasaki M, Mizunami M, Nishino H. (2017) Complete identification of four calycal giant interneurons in an insect brain. J. Comp. Neurol. 525:204–230.

9. Hosono S, Matsumoto Y, Mizunami M. (2016) Interaction of inhibitory and facilitatory effects of conditioning trials on long-term memory formation. Learning & Memory 23:669–678.

10. Matsumoto Y, Matsumoto CS, Takahashi T, Mizunami M. (2016) Activation of NO-cGMP signaling rescues age-related memory impairment in an insect. Front. Behav. Neurosci. 10:166.

11. Hamanaka Y, Minoura R, Nishino H, Miura T, Mizunami M. (2016) Dopamine- and tyrosine hydroxylase-immunoreactive neurons in the brain of the American cockroach, Periplaneta americana. PLoS One 11(8): e0160531.

12. Awata H, Wakuda R, Ishimaru Y, Matsuoka Y, Terao K, Katata S, Matsumoto Y, Hamanaka Y, Noji S, Mito T, Mizunami1 M. (2016) Roles of OA1 octopamine receptor and Dop1 dopamine receptor in mediating appetitive and aversive reinforcement revealed by RNAi studies. Sci. Rep. 6: 29696.

13. Yagi R, Mabuchi Y, Mizunami M, and Tanaka NK. (2016) Convergence of multimodal sensory pathways to the mushroom body calyx in Drosophila melanogaster. Sci. Rep. 6:29481

14. Sugimachi S, Matsumoto Y, Mizunami M, Okada J (2016) Effects of caffeine on olfactory learning in crickets. Zool. Sci. 33:513-519.

15. Koizumi M, Shigeno S, Mizunami M, Tanaka NK (2016) Three-dimensional brain atlas of pygmy squid, Idiosepius paradoxus. J. Comp. Neurol. 524: 2142-2157.

16. Awata H, Watanabe T, Hamanaka Y, Mito T, Noji S, Mizunami M. (2015) Knockout crickets for the study of learning and memory: Dopamine receptor Dop1 mediates aversive but not appetitive reinforcement in crickets. Sci. Rep. 5: 15885.

17. Matsumoto Y, Matsumoto CS, Wakuda R, Ichihara S, Mizunami M. (2015) Roles of octopamine and dopamine in appetitive and aversive memory acquisition studied in olfactory conditioning of maxillary palpi extension response in crickets. Front. Behav. Neurosci. 9:230.

18. Nishino H, Watanabe H, Kamimura I, Yokohari F, Mizunami M. (2015). Coarse topographic organization of pheromone-sensitive afferents from different antennal surfaces in the American cockroach. Neurosci. Lett. 595: 35-40.

19. Terao, K., Matsumoto, Y., & Mizunami, M. (2015). Critical evidence for the prediction error theory in associative learning. Scientific Reports, 5.

20. Mizunami M, Nemoto Y, Terao K, Hamanaka Y, Matsumoto Y. (2014) Roles of calcium/calmodulin-dependent kinase II in long-term memory formation in cricket. PLoS One 9: 9

21. Matsumoto Y, Sandoz JC, Devaud JM, Lormant F, Mizunami M, Giurfa M (2014) Cyclic nucleotide–gated channels, calmodulin, adenylyl cyclase and calcium/calmodulin-dependent kinase II are required for late but not early long-term memory formation in the honey bee. Learn. Mem. 21: 272-286.

22. Matsumoto Y., Hirashima D., Terao K., Mizunami M. (2013) Roles of NO signaling in long-term memory formation in visual learning in an insect PLoS One 8:e68538.

23. Matsumoto Y, Hirashima D, Mizunami M. (2013) Analysis and modepng of neural processes underlying sensory preconditioning. Neurobiol. Learn. Mem. 101: 103-113.

24. Matsumoto CS, Kuramochi T, Matsumoto Y, Watanabe H, Nishino H, Mizunami M. (2013) Participation of NO signapng in formation of long-term memory in sapvary conditioning of the cockroach. Neurosci. Lett. (in press)

25. Nishino H, Iwasaki M, Kamimura I, Mizunami M (2012) Divergent and convergent projections to the two parallel olfactory centers from two neighboring, pheromone-receptive glomerup in the male American cockroach. J. Comp. Neurol. 520: 342-3445.

26. Nishino H., Iwasaki M., Yasuyama K., Hongo H., Watanabe H. and Mizunami M. (2012) Visual and olfactory input segregation in the mushroom body calyces in a basal neopteran, the American cockroach. Arthropod Struct. Dev. 41: 3-16.

27. Matsumoto C.S., Matsumoto Y., Watanabe H., Nishino H. and Mizunami M. (2012) Context-dependent olfactory learning monitored by activities of sapvary neurons in cockroaches. Neurobiol. learn. Mem. 97: 30-36.

28. Nishino H., Iwasaki M., and Mizunami M. (2011) Pheromone detection by a pheromone emitter: a small, sex pheromone-specific processing system in the female American cockroach. Chem. Senses 36.261-270.

29. Watanabe H., Matsumoto SC., Nishino H. and Mizunami M. (2011) Critical roles of mecamylamine-sensitive mushroom body neurons in insect olfactory learning. Neurobiol. Learn. Mem. 95:1-13.

30. Watanabe H., Nishino H., Nishikawa M., Mizunami M. and Yokohari F. (2010) Complete mapping of glomeruli based on sensory nerve branching pattern in the primary olfactory center of the cockroach Periplaneta americana. J. Comp. Neurol.518: 3907-3930.

31. Yamagata N. and Mizunami M. (2010) Spatial representation of alarm pheromone information in a secondary olfactory center in the ant brain. Proc. R. Soc. B. 277: 2465-2475.

32. Nishino H., Yoritsune A., and Mizunami M. (2010) Postembryonic development of sexually dimorphic glomerup and related interneurons in the cockroach Periplaneta americana. Neurosci. Lett. 469: 60-64.

33. Yamagata N., Schmuker M., Szyszka P., Mizunami M., and Menzel R. (2009) Differential odor processing in two olfactory pathways in the honeybee. Frontiers Systems Neurosci. 3: 16.

34. Matsumoto Y., Hatano A., Unoki S. and Mizunami M. (2009) Stimulation of the cAMP system by the nitric oxide-cGMP system underlying the formation of long-term memory in an insect. Neurosci. Lett. 467:81-85.

35. Mizunami M., Unoki S., Mori Y., Hirashima D., Hatano A., and Matsumoto Y. (2009) Roles of octopaminergic and dopaminergic neurons in appetitive and aversive memory recall in an insect. BMC Biology 7:46.

36. Nakatani Y., Matsumoto Y., Mori Y., Hirashima D., Nishino H., Arikawa K. and Mizunami M. (2009) Why the carrot is more effective than the stick: Different dynamics of punishment memory and reward memory and its possible biological basis. Neurobiol. Learn. Mem. 92:370-380.

37. Nishino H., Yoritsune A., and Mizunami M. (2009) Different growth patterns of two adjacent glomerup responsible for sex-pheromone processing during postembryonic development of the cockroach Periplaneta americana. Neurosci. Lett. 462: 219-224.

38. Nishino H., Nishikawa M., Mizunami M., and Yokohari F. (2009) Functional and topographic segregation of glomerup revealed by local staining of antennal sensory neurons in the honeybee Apis melpfera. J. Comp. Neurol. 515: 161-180.

39. Takahashi T., Hamada A., Miyawaki K., Matsumoto Y., Mito T., Noji S., and Mizunami M. (2009) Systemic RNA interference for the study of learning and memory in an insect. J. Neurosci. Methods 179: 9-15.

40. Watanabe H., Sato C., Kuramochi T., Nishino H., and Mizunami M. (2008) Sapvary conditioning with antennal gustatory unconditioned stimulus in an insect. Neurobiol. Learn. Mem. 90: 245-254.

41. Nishino H. and Mizunami M. (2007) Both circumferential and longitudinal position of sensilla on an insect antennae influence afferent terminal location in glomerup. NeuroReport 18:1765-1769.

42. Yamagata N., Nishino H. and Mizunami M. (2007) Neural pathways for the processing of alarm pheromone in the ant brain. J. Comp. Neurol. 505: 424-442.

43. Watanabe H. and Mizunami M. (2007) Pavlov’s cockroach: classical conditioning of sapvation in an insect. PLoS ONE 6:e529.

44. Matsumoto Y. and Mizunami M. (2006) Olfactory memory capacity of the cricket Gryllus bimaculatus. Biol. Letters 2：608-610.

45. Unoki S., Matsumoto Y. and Mizunami M. (2006) Roles of octopaminergic and dopaminergic neurons in mediating reward and punishment signals in insect visual learning. Eur. J. Neurosci. 24: 2031-2038.

46. Nishino H. and Mizunami M. (2006) Termination profiles of insect chemosensory afferents in the antennal lobe are dependent on their origin on the flagellum. NeuroReport 17: 1303-1307.

47. Yamagata N., Nishino H. and Mizunami M. (2006) Pheromone-sensitive glomerup in the primary olfactory center of ants. Proc. R. Soc. B. 273: 2219-2225.

48. Fujiwara-Tsujii N. Yamagata N. Takeda T. Mizunami M. and Yamaoka R. (2006) Behavioral responses to the alarm pheromone of the ant Camponotus obscuripes (Hymenoptera: Formicidae). Zool. Sci. 23: 353-358.

49. Sato C. Matsumoto Y. Sakura M. and Mizunami M. (2006) Contextual olfactory learning in cockroaches. NeuroReport 17:553-557.

50. Watanabe H. and Mizunami M. (2006) Classical conditioning of activities of sapvary neurons in an insect. J. Exp. Biol. 209:766-779.

51. Matsumoto Y., Unoki S., Aonuma H., Mizunami M. (2006) Critical roles of the nitric oxide-cGMP cascade in the formation of cAMP-dependent long-term memory. Learn. Mem. 13:35-44.

52. Yamagata N., Fujiwara-Tsujii N., Yamaoka R. and Mizunami M. (2005) Pheromone communication and the mushroom body of the ant Camponotus obscuripes (Hymenoptera: Formicidae). Naturwissenshaften 92:532-536.

53. Unoki S., Matsumoto Y. and Mizunami M. (2005) Participation of octopaminergic reward system and dopaminergic punishment system in insect olfactory learning revealed by pharmacological study. Eur. J. Neurosci. 22: 1409-1416.

54. Nishino H., Nishikawa M., Yokohari F., and Mizunami M. (2005) Dual, multi-layered somatosensory maps formed by antennal tactile and contact chemosensory afferents in an insect brain. J. Comp. Neurol. 493: 291-308.

55. Matsumoto Y. and Mizunami M. (2004) Context-dependent olfactory learning in an insect.　Learn. Mem. 11: 288-293.

56. Watanabe H., Kobayashi Y., Sakura M., Matsumoto Y. and Mizunami M. (2003) Classical olfactory conditioning in the cockroach Periplaneta americana. Zool. Sci. 20: 1447-1454.

57. Matsumoto Y., Noji S. and Mizunami M. (2003) Time course of protein synthesis-dependent phase of olfactory memory in the cricket Gryllus bimaculatus. Zool. Sci. 20: 409-416.

58. Okada R., Sakura M. and Mizunami M. (2003) Distribution of dendrites of descending neurons and its imppcations for the basic organization of the cockroach brain. J. Comp. Neurol. 458: 158-174.

59. Nishino H., Yamashita S., Yamazaki Y. Nishikawa M., Yokohari F. and Mizunami M. (2003) Projection neurons originating from thermo- and hygrosensory glomerup in the antennal lobe of the cockroach. J. Comp. Neurol. 455: 40-55.

60. Sakura M., Okada R. and Mizunami M. (2002) Olfactory discrimination of structurally similar alcohols by cockroaches. J. Comp. Physiol. A. 188: 787-797.

61. Matsumoto Y. and Mizunami M. (2002) pfetime olfactory memory in the cricket Gryllus bimaculatus. J. Comp. Physiol. A. 188: 295-299.

62. Matsumoto Y. and Mizunami M. (2002) Temporal determinants of long-term retention of olfactory memory in the cricket Gryllus bimaculatus. J. Exp. Biol. 205: 1429-1437.

63. Sakura M. and Mizunami M. (2001) Olfactory learning and memory in the cockroach Periplaneta americana. Zool. Sci. 18: 21-28.

64. Matsumoto Y. and Mizunami M. (2000) Olfactory learning in the cricket Gryllus bimaculatus. J. Exp. Biol. 203: 2581-2588.

65. Okada R., Ikeda J. and Mizunami M. (1999) Sensory responses and movement-related activities in extrinsic neurons of the cockroach mushroom bodies. J. Comp. Physiol. A. 185: 115-129.

66. Iwasaki M., Mizunami M., Nishikawa M., Itoh T. and Tominaga Y. (1999) Ultrastructural analysis of modular subunits in the mushroom bodies of the cockroach. J. Electron Microsc. 48: 55-62.

67. Mizunami M., Weibrecht JM. and Strausfeld NJ. (1998) Mushroom bodies of the cockroach: Their participation in place memory. J. Comp. Neurol. 402: 520-537.

68. Mizunami M., Okada R., p Y. and Strausfeld N.J. (1998) Mushroom bodies of the cockroach: The activity and identities of neurons recorded in freely moving animals. J. Comp. Neurol. 402: 501-519.

69. Mizunami M., Iwasaki M., Okada R. and Nishikawa M. (1998) Topography of four classes of Kenyon cells in the mushroom bodies of the cockroach. J. Comp. Neurol. 399: 162-175.

70. Mizunami M., Iwasaki M., Okada R. and Nishikawa M. (1998) Topography of modular subunits in the mushroom bodies of the cockroach. J. Comp. Neurol. 399: 153-161.

71. Nishino H. and Mizunami M. (1998) Giant input neurons of the mushroom body: intracellular recording and staining in the cockroach. Neurosci. Lett. 246: 57-60.

72. Yamazaki Y., Nishikawa M. and Mizunami M. (1998) Three classes of GABA-pke immunoreactive neurons in the mushroom body of the cockroach. Brain Res. 788: 80-86.

73. Nishikawa M., Nishino H., Mizunami M. and Yokohari F. (1998) Function-specific distribution patterns of axon terminals of input neurons in the calyces of the mushroom body of the cockroach, Periplaneta americana. Neurosci. Lett. 245: 33-36.

74. Mizunami M., Iwasaki M., Nishikawa M. and Okada R. (1997) Modular structures in the mushroom body of the cockroach. Neurosci. Lett. 229: 153-156.

75. Mizunami M. (1996) Gain control of synaptic transfer from second- to third-order neurons of cockroach ocelp. J. Gen. Physiol. 107: 121-131.

76. Mizunami M. (1995) Morphology of higher-order ocellar interneurons in the cockroach brain. J. Comp. Neurol. 362: 293-304.

77. Mizunami M. (1995) Neural organization of ocellar pathways in the cockroach brain. J. Comp. Neurol. 352: 458-468.

78. Mizunami M. (1990) Synaptic rectification model equivalent to the correlation-type movement detector. Biol. Cybern. 64: 1-6.

79. pn J. T., Toh Y., Mizunami M. and Tateda H. (1990) Putative neurotransmitter in the ocellar neuropile of American cockroaches. Zool. Sci. 7: 593-603.

80. Mizunami M. (1990) Nonpnear signal transmission between second- and third-order neurons of cockroach ocelp. J. Gen. Physiol. 95: 297-317.

81. Mizunami M. and Tateda H. (1988) Synaptic transmission between second- and third-order neurones of cockroach ocelp. J. Exp. Biol. 140: 557-561.

82. Mizunami M. and Tateda H. (1988) Dynamic relationship between the slow potential and spikes in cockroach ocellar neurons. J. Gen. Physiol. 91: 703-723.

83. Mizunami M., Yamashita S. and Tateda H. (1987) Calcium-dependent action potentials in the second-order neurones of cockroach ocelp. J. Exp. Biol. 130: 259-274.

84. Mizunami M., Tateda H. and Naka K. -I. (1986) Dynamics of cockroach ocellar neurons. J. Gen. Physiol. 88: 275-292.

85. Mizunami M. and Tateda H. (1986) Classification of ocellar interneurones in the cockroach brain. J. Exp. Biol. 125: 57-70.

86. Mizunami M., Yamashita S. and Tateda H. (1982). Intracellular stainings of the large ocellar second-order neurons in the cockroach. J. Comp. Physiol. A. 149: 215-219.